人扁桃体内皮细胞说明：

              The tonsils are part of the lymphatic system and are located in the pharynx. The tonsils are the immune system’s first defense against foreign pathogens and help to prevent respiratory and gastrointestinal infections. Tonsil endothelial cells (TEC) line the blood vessels and actively participate in fluid balance, cellular transport, and immunity [1]. TEC also perform specialized functions for the tonsils including recruiting lymphocytes from the blood [2, 3]. Studies have shown that TEC express proteins that aid in lymphocyte adhesion and extravasation [3]. Morphological and physiological changes in human TEC (HTEC) can lead to the development of tonsillitis. HTEC are a useful model for studying inflammation in the tonsils.

             HTEC from ScienCell Research Laboratories are isolated from human tonsil. HTEC are cryopreserved at passage one and delivered frozen.  Each vial contains >5 x 10^5 cells in 1 ml volume. HTEC are characterized by immunofluorescence with antibodies specific to vWF/Factor VIII and CD31 (PECAM). HTEC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast, and fungi. HTEC are guaranteed to further expand for 10 population doublings under the conditions provided by ScienCell Research Laboratories. 

推荐培养基: 内皮细胞培养基(ECM, Cat. No. 1001)

产品使用说明：仅供科研研究使用

[2] Garrafa E, Alessandri G, Benetti A, Turetta D, Corradi A, Cantoni A, Cervi E, Bonardelli S, Parati E, Giulini S, Ensoli B, Caruso A. (2006) "Isolation and characterization of lymphatic microvascular endothelial cells from human tonsils". J Cell Physiol. 207(1): 107-113. 

[3] Palmeri D, Zuo F, Rosen S, Hemmerich S. (2004) "Differential gene expression profile of human tonsil high endothelial cells: implications for lymphocyte trafficking." J Leukoc Biol. 75(5): 910-927.