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Calu-3人肺腺癌 (胸水) (STR鉴定)
英文名:Calu-3
货号:ZQ0392
价格:¥1600.00
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推荐组合

Calu-3人肺腺癌 (胸水) (STR鉴定)

¥1600.00
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Calu-3人肺腺癌 (胸水)专用培养基

¥350.00 ¥450.00

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细胞套餐惊爆价

¥1950 ¥2050.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

Calu-3人肺腺癌 (胸水)

货号

ZQ0392

产品介绍

Calu-3上皮细胞分离自肺组织,所述肺组织来源于25岁的患有肺腺癌的白人男性患者,该患者先前接受了环磷酰胺、博莱霉素和阿霉素的治疗。该细胞系对于新型冠状病毒的体外繁殖是有价值的,是合适的转染宿主,并且在癌症和毒理学研究中具有应用。

注意事项:
(1)Calu-3细胞难消化,胰酶消化细胞应该以细胞变圆脱落冲散即可。
(2)该细胞形态不均一,有一些含有液泡的巨大细胞。细胞胞体有黑色颗粒物,属正常现象。

种属

性别/年龄

男/25岁

组织

肺腺癌;来源于转移部位:胸腔积液

疾病

腺癌

细胞类型

肿瘤细胞

形态学

上皮的

生长方式

贴壁

倍增时间

大约35~84小时

培养基和添加剂

MEM(含NEAA)(品牌:中乔新舟  货号:ZQ-300)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0392

生物安全等级

BSL-1

STR位点信息

Amelogenin: X

CSF1PO: 11,12

D13S317: 12

D16S539: 12,14

D5S818: 11

D7S820: 10,11

TH01: 6,9.3

TPOX: 8

vWA: 16,17

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 

基因表达

 

保藏机构

ATCC; HTB-55 BCRJ; 0264

供应限制

仅供科研使用

货号

ZQ0392

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: Active components in Ephedra sinica stapf disrupt the interaction between ACE2 and SARS-CoV-2 RBD: Potent COVID-19 therapeutic agents
DOI: 10.1016/j.jep.2021.114303
发表时间: 2021-06-05
期刊: JOURNAL OF ETHNOPHARMACOLOGY
影响因子: 4.36
货号: ZQ0392
产品名称: Human airway epithelial cells (Calu-3)

原文链接: https://www.sciencedirect.com/science/article/pii/S0378874121005304



PubMed=327080; DOI=10.1093/jnci/59.1.221
Fogh J., Fogh J.M., Orfeo T.
One hundred and twenty-seven cultured human tumor cell lines producing tumors in nude mice.
J. Natl. Cancer Inst. 59:221-226(1977)


PubMed=7459858
Rousset M., Zweibaum A., Fogh J.
Presence of glycogen and growth-related variations in 58 cultured human tumor cell lines of various tissue origins.
Cancer Res. 41:1165-1170(1981)


PubMed=6220172
Dracopoli N.C., Fogh J.
Polymorphic enzyme analysis of cultured human tumor cell lines.
J. Natl. Cancer Inst. 70:469-476(1983)


PubMed=3518877; DOI=10.3109/07357908609038260
Fogh J.
Human tumor lines for cancer research.
Cancer Invest. 4:157-184(1986)


PubMed=3940644
Brower M., Carney D.N., Oie H.K., Gazdar A.F., Minna J.D.
Growth of cell lines and clinical specimens of human non-small cell lung cancer in a serum-free defined medium.
Cancer Res. 46:798-806(1986)


PubMed=3129183
Hubbard W.C., Alley M.C., McLemore T.L., Boyd M.R.
Evidence for thromboxane biosynthesis in established cell lines derived from human lung adenocarcinomas.
Cancer Res. 48:2674-2677(1988)


PubMed=3335022
Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
Cancer Res. 48:589-601(1988)


PubMed=7515578; DOI=10.1152/ajplung.1994.266.5.L493
Shen B.-Q., Finkbeiner W.E., Wine J.J., Mrsny R.J., Widdicombe J.H.
Calu-3: a human airway epithelial cell line that shows cAMP-dependent Cl-secretion.
Am. J. Physiol. 266:L493-L501(1994)


PubMed=9636188; DOI=10.1073/pnas.95.13.7556
Kaplan D.H., Shankaran V., Dighe A.S., Stockert E., Aguet M., Old L.J., Schreiber R.D.
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice.
Proc. Natl. Acad. Sci. U.S.A. 95:7556-7561(1998)


PubMed=10523844; DOI=10.1038/sj.onc.1202957
Agochiya M., Brunton V.G., Owens D.W., Parkinson E.K., Paraskeva C., Keith W.N., Frame M.C.
Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.
Oncogene 18:5646-5653(1999)


PubMed=11064206; DOI=10.1016/S0378-5173(00)00452-X
Foster K.A., Avery M.L., Yazdanian M., Audus K.L.
Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery.
Int. J. Pharm. 208:1-11(2000)


PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)


PubMed=17483357; DOI=10.1158/0008-5472.CAN-06-4495
Tooker P., Yen W.-C., Ng S.-C., Negro-Vilar A., Hermann T.W.
Bexarotene (LGD1069, Targretin), a selective retinoid X receptor agonist, prevents and reverses gemcitabine resistance in NSCLC cells by modulating gene amplification.
Cancer Res. 67:4425-4433(2007)


PubMed=18083107; DOI=10.1016/j.cell.2007.11.025
Rikova K., Guo A.-L., Zeng Q.-F., Possemato A., Yu J., Haack H., Nardone J., Lee K., Reeves C., Li Y., Hu Y.-R., Tan Z.-P., Stokes M.P., Sullivan L., Mitchell J., Wetzel R., MacNeill J., Ren J.-M., Yuan J., Bakalarski C.E., Villen J., Kornhauser J.M., Smith B., Li D.-Q., Zhou X.-M., Gygi S.P., Gu T.-L., Polakiewicz R.D., Rush J., Comb M.J.
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Cell 131:1190-1203(2007)


PubMed=19153074; DOI=10.1093/hmg/ddp034
Medina P.P., Castillo S.D., Blanco S., Sanz-Garcia M., Largo C., Alvarez S., Yokota J., Gonzalez-Neira A., Benitez J., Clevers H.C., Cigudosa J.C., Lazo P.A., Sanchez-Cespedes M.
The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer.
Hum. Mol. Genet. 18:1343-1352(2009)


PubMed=19472407; DOI=10.1002/humu.21028
Blanco R., Iwakawa R., Tang M.-Y., Kohno T., Angulo B., Pio R., Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)


PubMed=20090954; DOI=10.1371/journal.pone.0008729
Yoshikawa T., Hill T.E., Yoshikawa N., Popov V.L., Galindo C.L., Garner H.R., Peters C.J., Tseng C.-T.
Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection.
PLoS ONE 5:E8729-E8729(2010)


PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
Nature 463:893-898(2010)


PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)


PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x
Iwakawa R., Kohno T., Enari M., Kiyono T., Yokota J.
Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.
Cancer Sci. 101:1891-1896(2010)


PubMed=22460905; DOI=10.1038/nature11003
Barretina J.G., Caponigro G., Stransky N., Venkatesan K., Margolin A.A., Kim S., Wilson C.J., Lehar J., Kryukov G.V., Sonkin D., Reddy A., Liu M., Murray L., Berger M.F., Monahan J.E., Morais P., Meltzer J., Korejwa A., Jane-Valbuena J., Mapa F.A., Thibault J., Bric-Furlong E., Raman P., Shipway A., Engels I.H., Cheng J., Yu G.-Y.K., Yu J.-J., Aspesi P. Jr., de Silva M., Jagtap K., Jones M.D., Wang L., Hatton C., Palescandolo E., Gupta S., Mahan S., Sougnez C., Onofrio R.C., Liefeld T., MacConaill L.E., Winckler W., Reich M., Li N.-X., Mesirov J.P., Gabriel S.B., Getz G., Ardlie K., Chan V., Myer V.E., Weber B.L., Porter J., Warmuth M., Finan P., Harris J.L., Meyerson M.L., Golub T.R., Morrissey M.P., Sellers W.R., Schlegel R., Garraway L.A.
The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)


PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112
Byers L.A., Wang J., Nilsson M.B., Fujimoto J., Saintigny P., Yordy J., Giri U., Peyton M., Fan Y.-H., Diao L.-X., Masrorpour F., Shen L., Liu W.-B., Duchemann B., Tumula P., Bhardwaj V., Welsh J., Weber S., Glisson B.S., Kalhor N., Wistuba I.I., Girard L., Lippman S.M., Mills G.B., Coombes K.R., Weinstein J.N., Minna J.D., Heymach J.V.
Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
Cancer Discov. 2:798-811(2012)


PubMed=24207061; DOI=10.1186/1559-0275-10-16
Cerciello F., Choi M., Nicastri A., Bausch-Fluck D., Ziegler A., Vitek O., Felley-Bosco E., Stahel R.A., Aebersold R., Wollscheid B.
Identification of a seven glycopeptide signature for malignant pleural mesothelioma in human serum by selected reaction monitoring.
Clin. Proteomics 10:16.1-16.12(2013)



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