人肺动脉内皮细胞说明:
血管内皮细胞主要作用是维持血管的动态平衡。此细胞能合成和分泌凝血和纤溶系统中的活化和抑制因子,同时也能合成和分泌影响着血小板粘附和聚集的某些介质。内皮细胞还可以释放具有调控细胞增殖和血管壁张力功能的分子。人肺动脉内皮细胞上的腺苷受体被脂多糖激活后,会引起参与急性肺损伤的病生理过程的IL-6的释放。许多此类以及其他的作用过程可以应用培养的细胞在体外研究进行研究,人肺动脉内皮细胞正是这类研究中普遍应用的细胞类型。
人肺动脉内皮细胞(HPAEC)提取于人肺组织,原代冻存。每管含有细胞数>5×105 cells/ml,此细胞通过vWF/Factor VIII 和CD31 (P-CAM)免疫荧光染色验证,经测试不含有HIV-1、HBV、HCV、支原体、细菌、酵母和真菌。细胞可以达到15倍增。
推荐培养基: 内皮细胞培养基(ECM, Cat. No. 1001)
产品使用说明:仅供科研研究使用
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