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NCI-H520人肺鳞癌细胞(STR鉴定)
英文名:NCI-H520
货号:ZQ0014
价格:¥1800.00
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NCI-H520人肺鳞癌细胞(STR鉴定)

¥1800.00
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NCI-H520人肺鳞癌细胞专用培养基

¥350.00 ¥450.00

配套完培,省时省力,单买细胞无优惠

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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

NCI-H520人肺鳞癌细胞

货号

ZQ0014

产品介绍

NCI-H520是一种人肺鳞癌细胞系,最初由Gazdar AF等人在1982年从一名肺鳞状细胞癌患者的肺组织中分离建立。细胞呈上皮细胞样,贴壁生长,形态为多角形,呈岛状。是适合进行转染的宿主细胞,常用于肺癌的研究,包括药物筛选、基因功能研究和肿瘤生物学研究。

种属

性别/年龄

组织

疾病

鳞状细胞癌

生物安全等级

BSL-1

STR位点信息

Amelogenin: X

CSF1PO: 10

D13S317: 10,11

D16S539: 8,13

D5S818: 12,13

D7S820: 8,12

TH01: 10

TPOX: 8

vWA: 18,19

细胞类型

肿瘤细胞 

形态学

上皮细胞样

生长方式

贴壁

倍增时间

大约25~61小时

培养基和添加剂

RPMI-1640(货号:ZQ-200)+10%胎牛血清(货号:ZQ0500)+1%双抗(货号:CSP006

推荐完全培养基货号

ZM0014 

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

ATCC

供应限制

仅供科研使用

货号

ZQ0014

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


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High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH.
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Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.
Cell 131:1190-1203(2007)


14、PubMed=19472407; DOI=10.1002/humu.21028
Blanco R., Iwakawa R., Tang M.-Y., Kohno T., Angulo B., Pio R., Montuenga L.M., Minna J.D., Yokota J., Sanchez-Cespedes M.
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)


15、PubMed=20164919; DOI=10.1038/nature08768
Bignell G.R., Greenman C.D., Davies H., Butler A.P., Edkins S., Andrews J.M., Buck G., Chen L., Beare D., Latimer C., Widaa S., Hinton J., Fahey C., Fu B.-Y., Swamy S., Dalgliesh G.L., Teh B.T., Deloukas P., Yang F.-T., Campbell P.J., Futreal P.A., Stratton M.R.
Signatures of mutation and selection in the cancer genome.
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16、PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
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A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
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Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.
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18、PubMed=22460905; DOI=10.1038/nature11003
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.
Nature 483:603-607(2012)


19、PubMed=22961666; DOI=10.1158/2159-8290.CD-12-0112
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Proteomic profiling identifies dysregulated pathways in small cell lung cancer and novel therapeutic targets including PARP1.
Cancer Discov. 2:798-811(2012)


20、PubMed=24002593; DOI=10.1038/bjc.2013.452
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Gene-expression data integration to squamous cell lung cancer subtypes reveals drug sensitivity.
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21、PubMed=25485619; DOI=10.1038/nbt.3080
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22、PubMed=25877200; DOI=10.1038/nature14397
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23、PubMed=26589293; DOI=10.1186/s13073-015-0240-5
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24、PubMed=27397505; DOI=10.1016/j.cell.2016.06.017
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25、PubMed=27602502; DOI=10.18632/oncotarget.11845
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27、PubMed=29681454; DOI=10.1016/j.cell.2018.03.028
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28、PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
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29、PubMed=30971826; DOI=10.1038/s41586-019-1103-9
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30、PubMed=31068700; DOI=10.1038/s41586-019-1186-3
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Next-generation characterization of the Cancer Cell Line Encyclopedia.
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31、PubMed=31803961; DOI=10.1002/jcb.29564
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From clinical specimens to human cancer preclinical models -- a journey the NCI-cell line database-25 years later.
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32、PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
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Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)


33、PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
Goncalves E., Poulos R.C., Cai Z.-X., Barthorpe S., Manda S.S., Lucas N., Beck A., Bucio-Noble D., Dausmann M., Hall C., Hecker M., Koh J., Lightfoot H., Mahboob S., Mali I., Morris J., Richardson L., Seneviratne A.J., Shepherd R., Sykes E., Thomas F., Valentini S., Williams S.G., Wu Y.-X., Xavier D., MacKenzie K.L., Hains P.G., Tully B., Robinson P.J., Zhong Q., Garnett M.J., Reddel R.R.
Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)


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36、Brower M, et al. Growth of cell lines and clinical specimens of human non-small cell lung cancer in a serum-free defined medium. Cancer Res. 46: 798-806, 1986. PubMed: 3940644

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