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AGS人胃腺癌细胞(STR鉴定)
英文名:AGS
货号:ZQ0240
价格:¥1200.00
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推荐组合

AGS人胃腺癌细胞(STR鉴定)

¥1200.00
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AGS人胃腺癌细胞专用培养基

¥350.00 ¥500.00

配套完培,省时省力,单买细胞无优惠

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细胞套餐惊爆价

¥1550 ¥1700.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

AGS人胃腺癌细胞

货号

ZQ0240

产品介绍

AGS 细胞是一种人类胃腺癌细胞系,来源于一名 54 岁白人女性的胃组织一个未经治疗的切除肿瘤碎块。它们广泛用于以胃癌为重点的生物医学研究,包括癌细胞生物学、发病机制和药物测试研究。
AGS 细胞系表现出上皮样形态,其特点是其侵袭性生长模式和体内致瘤潜力。这些细胞通常用作研究胃癌分子和细胞机制的模型,包括众所周知的胃癌风险因素幽门螺杆菌感染的影响。AGS 细胞提供了一个强大的系统来探索胃癌细胞与幽门螺杆菌之间的相互作用,特别是关于细菌因素如何影响癌细胞增殖、凋亡和炎症反应。
AGS 细胞还可用于研究胃上皮屏障对各种刺激(包括炎性细胞因子)的反应,以及研究与胃癌有关的信号通路,例如涉及 NF-kB、Wnt 和 MAPK 的信号通路。它们的实用性还扩展到评估新的治疗剂,用于评估抗癌药物、靶向疗法和具有潜在抗癌特性的天然化合物的功效和作用机制。
此外,AGS 细胞通常用于旨在了解胃癌的遗传和表观遗传改变的研究,为这种具有挑战性且经常致命的疾病提供潜在的诊断标记和治疗靶点。

注意事项:
(1)AGS细胞低密度时呈上皮样细胞,细胞高密度会出现部分圆形贴壁细胞。
(2)细胞生长80%即可传代。

种属

性别/年龄

女/54岁

组织

疾病

胃腺癌

细胞类型

肿瘤细胞

形态学

上皮细胞

生长方式

贴壁

倍增时间

大约20~24.16小时 

培养基和添加剂

F12K基础培养基(中乔新舟 货号:ZQ-599 )+10%胎牛血清(中乔新舟 货号:ZQ500-A)+1%双抗(中乔新舟 货号:CSP006

推荐完全培养基货号

ZM0240

生物安全等级

BSL-2

STR位点信息

Amelogenin: X
CSF1PO: 11,12
D13S317: 12
D16S539: 11,13
D5S818: 9,12
D7S820: 10,11
TH01: 6,7
TPOX: 11,12
vWA: 16,17
FGA: 23,24
D3S1358: 16
D21S11: 29
Penta_D: 9,10
Penta_E: 13,16
D18S51: 13
D8S1179: 13
D19S433: 13.2,16
D2S1338: 20,22

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

ATCC; CRL-1739 BCRC; 60102 BCRJ; 0311

供应限制

仅供科研使用


货号

ZM0240

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*2支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: Silencing LINC01021 inhibits gastric cancer through upregulation of KISS1 expression by blocking CDK2-dependent phosphorylation of CDX2
DOI: 10.1016/j.omtn.2021.01.025
发表时间: 2021-01-26
期刊: Molecular Therapy-Nucleic Acids
影响因子: 8.886
货号: ZQ0240
产品名称: AGS cells
原文链接: https://www.sciencedirect.com/science/article/pii/S2162253121000251


论文标题: LRG1 mediated by ATF3 promotes growth and angiogenesis of gastric cancer by regulating the SRC/STAT3/VEGFA pathway
DOI: 10.1007/s10120-022-01279-9
发表时间: 2022-01-30
期刊: Gastric Cancer
影响因子: 7.37
货号: ZQ0240
产品名称: AGS cells
原文链接: https://link.springer.com/article/10.1007/s10120-022-01279-9


论文标题: Orphan nuclear receptor Nurr1 promotes Helicobacter pylori-associated gastric carcinogenesis by directly enhancing CDK4 expression
DOI: 10.1016/j.ebiom.2020.102672
发表时间: 2020-02-27
期刊: EBioMedicine
影响因子: 5.736
货号: ZQ0240
产品名称: AGS cells

原文链接: https://www.sciencedirect.com/science/article/pii/S2352396420300475


论文标题: Isorhamnetin Promotes MKN-45 Gastric Cancer Cell Apoptosis by Inhibiting PI3K-Mediated Adaptive Autophagy in a Hypoxic Environment
DOI: 10.1021/acs.jafc.1c02620
发表时间: 2021-07-16
期刊: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
影响因子: 5.279
货号: ZQ0240
产品名称: AGS cells
原文链接: https://pubs.acs.org/doi/abs/10.1021/acs.jafc.1c02620


论文标题: HDAC3-dependent transcriptional repression of FOXA2 regulates FTO/m6A/MYC signaling to contribute to the development of gastric cancer
DOI: 10.1038/s41417-020-0193-8
发表时间: 2020-07-13
期刊: CANCER GENE THERAPY
影响因子: 4.534
货号: ZQ0240
产品名称: AGS cells
原文链接: https://www.nature.com/articles/s41417-020-0193-8



论文标题: Up-regulation of DGAT1 in cancer tissues and tumor-infiltrating macrophages influenced survival of patients with gastric cancer
DOI: 10.1186/s12885-021-07976-5
发表时间: 2021-03-09
期刊: BMC CANCER
影响因子: 4.43
货号: ZQ0240
产品名称: AGS cells
原文链接: https://bmccancer.biomedcentral.com/articles/10.1186/s12885-021-07976-5



论文标题: Targeting ADAR1 suppresses progression and peritoneal metastasis of gastric cancer through Wnt / β-catenin pathway
DOI: 10.7150/jca.61031
发表时间: 2021-10-28
期刊: Journal of Cancer
影响因子: 4.207
货号: ZQ0240
产品名称: AGS cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734406/


论文标题: Ubiquitin-associated protein 2 like (UBAP2L) enhances growth and metastasis of gastric cancer cells
DOI: 10.1080/21655979.2021.1982308
发表时间: 2021-11-25
期刊: Bioengineered
影响因子: 3.269
货号: ZQ0240
产品名称: AGS cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/21655979.2021.1982308


论文标题: Dihydroartemisinin suppresses proliferation, migration, the Wnt/β‑catenin pathway and EMT via TNKS in gastric cancer Corrigendum in /10.3892/ol.2021.13152
DOI: 10.3892/ol.2021.12949
发表时间: 2021-07-29
期刊: Oncology Letters
影响因子: 2.967
货号: ZQ0240
产品名称: AGS cells
原文链接: https://www.spandidos-publications.com/10.3892/ol.2021.12949


论文标题: Knockdown of lncRNA SNHG4 suppresses gastric cancer cell proliferation and metastasis by targeting miR-204-5p.
DOI: 10.4149/neo_2021_200914n981
发表时间: 2021-02-11
期刊: NEOPLASMA
影响因子: 2.575
货号: ZQ0240
产品名称: "human gastric
cancer cell lines AGS"
原文链接: https://europepmc.org/article/med/33567852?javascript_support=no


论文标题: Nucleoporin 37 promotes the cell proliferation, migration, and invasion of gastric cancer through activating the PI3K/AKT/mTOR signaling pathway
DOI: 10.1007/s11626-021-00627-w
发表时间: 2021-12-09
期刊: IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL
影响因子: 2.416
货号: ZQ0240
产品名称: AGS cell lines
原文链接: https://link.springer.com/article/10.1007/s11626-021-00627-w


论文标题: Knockdown of Serum- and Glucocorticoid-Regulated Kinase 1 Enhances Cisplatin Sensitivity of Gastric Cancer Through Suppressing the Nuclear Factor Kappa-B Signaling Pathway.
DOI: 10.5152/balkanmedj.2021.21114
发表时间: 2021-11-01
期刊: Balkan Medical Journal
影响因子: 2.021
货号: ZQ0240
产品名称: AGS cell lines
原文链接: https://europepmc.org/article/med/34860160?javascript_support=no


论文标题: Bmi-1 directly upregulates glucose transporter 1 in human gastric adenocarcinoma
DOI: 10.1515/biol-2022-0024
发表时间: 2022-01-01
期刊: Open Life Sciences
影响因子: 0.938
货号: ZQ0240
产品名称: human GAC AGS cells

原文链接: https://www.degruyter.com/document/doi/10.1515/biol-2022-0024/html



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Cancer Cell 40:835-849.e8(2022)

公司简介 / Company profile
上海中乔新舟生物科技有限公司
Shanghai Zhong Qiao Xin Zhou Biotechnology Co.,Ltd.
      上海中乔新舟生物科技有限公司(官网:www.zqxzbio.com)成立于2011年,历经十多年发展,主要专注于细胞生物学产品的研究和开发,专...
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