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B-CPAP人甲状腺癌细胞(STR鉴定)
英文名:B-CPAP
货号:ZQ0304
价格:¥1800.00
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推荐组合

B-CPAP人甲状腺癌细胞(STR鉴定)

¥1800.00
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B-CPAP人甲状腺癌细胞专用培养基

¥700.00

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细胞套餐惊爆价

¥2500
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

B-CPAP人甲状腺癌细胞

货号

ZQ0304

产品介绍

B-CPAP 是一种人类乳头状甲状腺癌细胞系,于1992年从一名罹患转移性甲状腺乳头状癌的76岁女性的肿瘤组织中建立。该细胞系表现出上皮样形态,常用于研究甲状腺癌生物学,包括肿瘤发生和转移机制。B-CPAP 细胞因携带 BRAF V600E 突变而著名,这是一种与侵袭性甲状腺癌相关的常见基因变异,是评估 BRAF 抑制剂作为治疗剂的关键模型。

除了 BRAF 突变外,B-CPAP 细胞还表达甲状腺特异性标志物,如甲状腺球蛋白和促甲状腺激素受体,使其成为研究甲状腺功能和病理的宝贵模型。它们已广泛用于研究与甲状腺癌进展有关的信号通路,包括 MAPK/ERK 通路激活。这些细胞还用于药物耐药性和细胞凋亡研究,为甲状腺癌治疗失败的机制提供了见解。

种属

性别/年龄

女/76岁

组织

甲状腺

疾病

甲状腺癌

细胞类型

肿瘤细胞 

形态学

纺锤状或圆形细胞贴壁生长成单层细胞

生长方式

贴壁

倍增时间

大约30小时 

培养基和添加剂

RPMI-1640(中乔新舟 货号:ZQ-200)+10%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟  货号:CSP006)+1%Non-essential Amino Acids, 100X (中乔新舟  货号:CSP008)+ +1% Sodium Pyruvate 100 mM Solution(中乔新舟  货号:CSP003)+1%L-alanyl-L-glutamine(中乔新舟   货号:CSP004

推荐完全培养基货号

ZM0304

生物安全等级

BSL-1

STR位点信息

Amelogenin: X;

CSF1PO: 13
D2S1338:18
D3S1358:16,17
D5S818: 10,11
D7S820: 10
D8S1179:12,13
D13S317:12
D16S539:11,12
D18S51: 13,17
D19S433:13.2,15 (PubMed=25877200)
             :14,15 (DSMZ=ACC-273)
D21S11: 30 (DSMZ=ACC-273)
           :30,31.2 (PubMed=18713817; PubMed=25877200; PubMed=30737244)
FGA:20,23
Penta D: 10,11
Penta E: 5,12 (DSMZ=ACC-273)
            :5,12,17 (PubMed=25877200)
TH01:6,9.3
TPOX:8,11
vWA:14,17

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

*** 

基因表达

*** 

保藏机构

DSMZ; ACC-273

供应限制

仅供科研使用


货号

ZQ0304

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: Hypomethylated gene RAC3 induces cell proliferation and invasion by increasing FASN expression in endometrial cancer
DOI:10.1016/j.biocel.2022.106274. Epub 2022 Jul 30
发表时间: 2022-8-1
期刊: The International Journal of Biochemistry & Cell Biology
影响因子: 3.4
货号: ZQ0304
产品名称:  BCPAP cells
原文链接:https://www.sciencedirect.com/science/article/abs/pii/S1357272522001194?via%3Dihub


论文标题: Identification and Application of an Aptamer Targeting Papillary Thyroid Carcinoma Using Tissue-SELEX

DOI: 10.1021/acs.analchem.9b01000
发表时间: 2019-05-29
期刊: ANALYTICAL CHEMISTRY
影响因子: 6.35
货号: ZQ0304
产品名称: BCPAP cells

原文链接: https://pubs.acs.org/doi/abs/10.1021/acs.analchem.9b01000



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