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C-33 A人子宫颈癌(STR鉴定)
英文名:C-33A
货号:ZQ0359
价格:¥1350.00
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推荐组合

C-33 A人子宫颈癌(STR鉴定)

¥1350.00
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C-33 A人子宫颈癌专用培养基

¥350.00 ¥480.00

配套完培,组合使用,省时省力

=

细胞套餐惊爆价

¥1700 ¥2080.00
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

C-33 A人子宫颈癌

货号

ZQ0359

产品介绍

C-33A细胞起源于一名诊断为子宫癌的66岁白人女性的宫颈组织。该细胞系的特点是TP53基因发生了独特的遗传改变,密码子273处的点突变导致精氨酸向半胱氨酸的替代,从而导致p53蛋白的表达升高。这种突变在细胞的病理生理中起关键作用,影响其生长特性和致瘤潜能。
另外c - 33a细胞被证实具有致瘤性。当引入免疫缺陷裸鼠时,这些细胞具有形成未分化癌的能力,这突出了它们在癌症研究中的应用,特别是在旨在了解宫颈癌肿瘤发生和进展机制的研究中。此外,这些细胞对人乳头瘤病毒(HPV)的DNA和RNA都是阴性的,这将它们与许多其他经常携带HPV整合物的宫颈癌细胞系区分开来。这方面使得c - 33a细胞在研究独立于HPV感染发展的宫颈癌方面特别有价值,为癌症发生的其他途径提供了见解。

注意事项:
C-33 A细胞低密度生长为上皮样多边形细胞,高密度状态时有圆细胞和多边形细胞两种贴壁细胞形态。

种属

性别/年龄

女/66岁

组织

子宫颈

疾病

细胞类型

上皮,视网膜母细胞瘤

形态学

上皮细胞

生长方式

贴壁

该细胞易形成多层堆叠,上层细胞为圆形透亮的,也是活细胞,不影响传代及增殖

倍增时间

大约32.64小时 

培养基和添加剂

MEM(含有NEAA)(中乔新舟  货号:ZQ-300+10%FBS(中乔新舟  货号:ZQ500-A+1%PS(中乔新舟  货号:CSP006

推荐完全培养基货号

ZM0359

生物安全等级

BSL-1

STR位点信息

Amelogenin: X

CSF1PO: 12

D13S317: 13

D16S539: 13,14

D5S818: 11,12

D7S820: 10

TH01: 7,8

TPOX: 9

vWA: 18,20

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 ***

基因表达

 ***

保藏机构

ATCC; HTB-31 ATCC; CRM-HTB-31 BCRC; 60554 BCRJ; 0348

供应限制

仅供科研使用

货号

ZQ0359

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: Circular RNA hsa_circ_0043280 inhibits cervical cancer tumor growth and metastasis via miR-203a-3p/PAQR3 axis
DOI: 10.1038/s41419-021-04193-7
发表时间: 2021-09-29
期刊: Cell Death & Disease
影响因子: 8.469
货号: ZQ0359
产品名称: C33A cells
原文链接: https://www.nature.com/articles/s41419-021-04193-7


论文标题: LncRNA SOX2OT affects cervical cancer cell growth, migration and invasion by regulating SOX2
DOI: 10.1080/15384101.2020.1750812
发表时间: 2020-04-14
期刊: CELL CYCLE
影响因子: 3.699
货号: ZQ0359
产品名称: C-33A cells
原文链接: https://www.tandfonline.com/doi/abs/10.1080/15384101.2020.1750812


论文标题: Kindlin‑2 suppresses cervical cancer cell migration through AKT/mTOR‑mediated autophagy induction
DOI: 10.3892/or.2020.7603
发表时间: 2020-07-01
期刊: ONCOLOGY REPORTS
影响因子: 3.417
货号: ZQ0359
产品名称: C-33A cells
原文链接: https://www.spandidos-publications.com/10.3892/or.2020.7603


论文标题: MiRNA-211 triggers an autophagy-dependent apoptosis in cervical cancer cells: regulation of Bcl-2
DOI: 10.1007/s00210-019-01720-4
发表时间: 2019-10-21
期刊: NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
影响因子: 2.058
货号: ZQ0359
产品名称: C-33A cells

原文链接: https://link.springer.com/article/10.1007/s00210-019-01720-4



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Shanghai Zhong Qiao Xin Zhou Biotechnology Co.,Ltd.
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