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NIH:OVCAR-3人卵巢癌细胞(STR鉴定)
英文名:NIH:OVCAR-3
货号:ZQ0365
价格:¥1500.00
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NIH:OVCAR-3人卵巢癌细胞(STR鉴定)

¥1500.00
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NIH:OVCAR-3 [OVCAR3]人卵巢癌细胞专用培养基

¥850.00

配套完培,组合使用,省时省力!

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细胞套餐惊爆价

¥2350
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  • 产品说明
  • 产品规格
  • 参考文献
  • STR鉴定

产品名称

NIH:OVCAR-3人卵巢癌细胞

货号

ZQ0365

产品介绍

OVCAR-3细胞是一种人卵巢癌细胞系,建立于一名60岁白人女性患者的恶性腹水,该患者患有进展性卵巢腺癌,对环磷酰胺、阿霉素和顺铂治疗难治性。该细胞被广泛用于包括耐药在内的研究,特别是涉及DNA损伤反应生物标志物、同源重组修复、整体细胞周期动力学、癌细胞生物学和基因表达研究的研究。
该细胞在形态上是上皮细胞,具有较高的体外生长潜力和在免疫缺陷小鼠中形成肿瘤的能力。这些细胞表达卵巢癌的一些特征标记物,并被广泛用于卵巢癌的生物学研究。
OVCAR-3细胞的核型复杂,有大量的染色体异常,是典型的高级别浆液性卵巢癌。它是雌激素受体阳性,这在卵巢癌细胞系中相对少见,这一特征被用于研究激素对卵巢癌进展和治疗的影响。
总之,OVCAR-3细胞系是卵巢癌研究的基石,为研究高级别卵巢浆液腺癌的激素影响、耐药性和遗传基础之间复杂的相互作用提供了一个强大的模型。
预定此细胞需至少提前两周。

注意事项:
(1) 细胞长得比较慢,建议1:2传代,消化时间3-4分钟,6-7天左右即可传代。
(2) 细胞形态不均一,有一些含有液泡的巨大细胞,该细胞胞体有黑色颗粒物属正常现象。

种属

性别/年龄

女/60岁

组织

卵巢

疾病

腺癌

细胞类型

肿瘤细胞

形态学

上皮

生长方式

贴壁

倍增时间

 大约35~69小时

培养基和添加剂

RPMI-1640(中乔新舟 货号:ZQ-200+20%胎牛血清(中乔新舟 货号:ZQ0500)+1%P/S(中乔新舟  货号:CSP006)++0.01mg/mL牛胰岛素

推荐完全培养基货号

ZM0365

生物安全等级

BSL-1

STR位点信息

Amelogenin: X

CSF1PO: 11,12

D13S317: 12

D16S539: 12

D5S818: 11,12

D7S820: 10

TH01: 9,9.3

TPOX: 8

vWA: 17

培养条件

95%空气,5%二氧化碳;37℃

抗原表达/受体表达

 ***

基因表达

 ***

保藏机构

ATCC; HTB-161

供应限制

仅供科研使用

货号

ZQ0365

发货规格

活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一

发货形式

活细胞:常温运输;冻存管:干冰运输

储存温度

活细胞:培养箱;冻存管:液氮罐

产地

中国

供应限制

仅供科研使用


论文标题: Six-transmembrane epithelial antigen of the prostate 1 expression promotes ovarian cancer metastasis by aiding progression of epithelial-to-mesenchymal transition
DOI: 10.1007/s00418-020-01877-7
发表时间: 2020-05-07
期刊: HISTOCHEMISTRY AND CELL BIOLOGY
影响因子: 4.304
货号: ZQ0365
产品名称: OVCAR-3 cells
原文链接: https://link.springer.com/content/pdf/10.1007/s00418-020-01877-7.pdf


论文标题: Long non-coding RNA EPB41L4A-AS2 suppresses progression of ovarian cancer by sequestering microRNA-103a to upregulate transcription factor RUNX1T1
DOI: 10.1113/EP087847
发表时间: 2019-12-09
期刊: EXPERIMENTAL PHYSIOLOGY
影响因子: 2.624
货号: ZQ0365
产品名称: OVCAR-3 cells
原文链接: https://physoc.onlinelibrary.wiley.com/doi/abs/10.1113/EP087847


论文标题: Circular RNA profiling reveals circRNA1656 as a novel biomarker in high grade serous ovarian cancer
DOI: 10.5582/bst.2019.01021
发表时间: 2019-05-12
期刊: BioScience Trends
影响因子: 1.686
货号: ZQ0365
产品名称: OVCAR-3 cells

原文链接: https://www.jstage.jst.go.jp/article/bst/13/2/13_2019.01021/_article/-char/ja/



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