产品名称 |
MDA-MB-468人乳腺癌细胞 |
货号 |
ZQ0373 |
产品介绍 |
1977年由R. Cailleau等从一位患有乳腺癌的51岁黑人女性转移癌胸水中分离得到。虽然供组织者的G6PD等位基因杂合,但此细胞株始终表现为G6PD A表型。 注意事项:
MDA-MB-468细胞使用的L-15基础培养液必须在没有CO2平衡的环境中培养细胞。不能在普通的5% CO2细胞培养箱中培养。 如果发现细胞生长缓慢,可提高血清含量至20%。 |
种属 |
人 |
性别/年龄 |
女/51岁 |
组织 |
乳腺/乳房;来源于转移部位:胸腔积液 |
疾病 |
腺癌 |
细胞类型 |
肿瘤细胞 |
形态学 |
上皮 |
生长方式 |
贴壁 |
倍增时间 |
大约30~79.76小时 |
培养基和添加剂 |
L-15(中乔新舟 货号:ZQ-1100)+10%FBS(中乔新舟 货号:ZQ500-S)+1%P/S(中乔新舟 货号:CSP006) |
推荐完全培养基货号 |
|
生物安全等级 |
BSL-1 |
STR位点信息 |
Amelogenin: X CSF1PO: 12 D13S317: 12 D16S539: 9 D5S818: 12 D7S820: 8 TH01: 7 TPOX: 8,9 vWA: 18 |
培养条件 |
100%空气;37℃ |
抗原表达/受体表达 |
*** |
基因表达 |
*** |
保藏机构 |
ATCC; HTB-132 DSMZ; ACC-738 |
供应限制 |
仅供科研使用 |
货号 |
ZQ0373 |
发货规格 |
活细胞:T25培养瓶*1瓶或者1ml 冻存管*1支(细胞量约为5 x 10^5 cells/vial)二选一 |
发货形式 |
活细胞:常温运输;冻存管:干冰运输 |
储存温度 |
活细胞:培养箱;冻存管:液氮罐 |
产地 |
中国 |
供应限制 |
仅供科研使用 |
论文标题: Triple-serotype chimeric oncolytic adenovirus exerts multiple synergistic mechanisms against solid tumors
DOI: 10.1136/jitc-2022-004691
发表时间: 2022-05-01
期刊: Journal for ImmunoTherapy of Cancer
影响因子: 13.751
货号: ZQ0373
产品名称: MBA-MB-468 cells
原文链接: https://jitc.bmj.com/content/10/5/e004691.abstract
论文标题: The m6A methyltransferase METTL3 controls epithelial-mesenchymal transition, migration and invasion of breast cancer through the MALAT1/miR-26b/HMGA2 axis
DOI: 10.1186/s12935-021-02113-5
发表时间: 2021-08-21
期刊: Cancer Cell International
影响因子: 5.722
货号: ZQ0373
产品名称: MDA-MB-468 cell
原文链接: https://link.springer.com/article/10.1186/s12935-021-02113-5
论文标题: The long noncoding RNA TINCR promotes breast cancer cell proliferation and migration by regulating OAS1
DOI: 10.1038/s41420-021-00419-x
发表时间: 2021-03-01
期刊: Cell Death Discovery
影响因子: 5.241
货号: ZQ0373
产品名称: MDA-MB-468 cell
原文链接: https://www.nature.com/articles/s41420-021-00419-x
论文标题: Development of a Prognostic Model Based on the Identification of EMT-Related lncRNAs in Triple-Negative Breast Cancer
DOI: 10.1155/2021/9219961
发表时间: 2021-11-27
期刊: Journal of Oncology
影响因子: 4.375
货号: ZQ0373
产品名称: MDA-MB-468 cell
原文链接: https://www.hindawi.com/journals/jo/2021/9219961/
论文标题: Long Non-Coding RNA A2M-AS1 Promotes Breast Cancer Progression by Sponging microRNA-146b to Upregulate MUC19
DOI: 10.2147/IJGM.S278564
发表时间: 2020-11-27
期刊: International Journal of General Medicine
影响因子: 1.927
货号: ZQ0373
产品名称: MDA-MB-468 cells
原文链接: https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7708314/
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Behan F.M., Iorio F., Picco G., Goncalves E., Beaver C.M., Migliardi G., Santos R., Rao Y., Sassi F., Pinnelli M., Ansari R., Harper S., Jackson D.A., McRae R., Pooley R., Wilkinson P., van der Meer D.J., Dow D., Buser-Doepner C.A., Bertotti A., Trusolino L., Stronach E.A., Saez-Rodriguez J., Yusa K., Garnett M.J.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature 568:511-516(2019)
PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)
PubMed=31978347; DOI=10.1016/j.cell.2019.12.023
Nusinow D.P., Szpyt J., Ghandi M., Rose C.M., McDonald E.R. III, Kalocsay M., Jane-Valbuena J., Gelfand E.T., Schweppe D.K., Jedrychowski M.P., Golji J., Porter D.A., Rejtar T., Wang Y.K., Kryukov G.V., Stegmeier F., Erickson B.K., Garraway L.A., Sellers W.R., Gygi S.P.
Quantitative proteomics of the Cancer Cell Line Encyclopedia.
Cell 180:387-402.e16(2020)
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Finlay-Schultz J., Jacobsen B.M., Riley D., Paul K.V., Turner S., Ferreira-Gonzalez A., Harrell J.C., Kabos P., Sartorius C.A.
New generation breast cancer cell lines developed from patient-derived xenografts.
Breast Cancer Res. 22:68.1-68.12(2020)
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Kuiken H.J., Dhakal S., Selfors L.M., Friend C.M., Zhang T., Callari M., Schackmann R.C.J., Gray G.K., Crowdis J., Bhang H.-E.C., Baslan T., Stegmeier F., Gygi S.P., Caldas C., Brugge J.S.
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Oncogene 41:112-124(2022)
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