产品名称	ES-2人卵巢透明细胞癌细胞
货号	ZQ0067
产品介绍	ES-2细胞系是从一名47岁的黑人妇女的外科肿瘤标本中建立的。该肿瘤被描述为低分化卵巢透明细胞癌。最初，细胞生长在软琼脂中。在裸鼠中成瘤。 该细胞对多种化疗药物包括doxorubicin, cisplatin, carmustine, etoposide 和cyanomorpholinodoxorubicin (MRA-CN)表现出低到中等的耐受性。 ES-2细胞表达低水平的P糖蛋白。
种属	人
性别/年龄	女/47岁
组织	卵巢
疾病	卵巢透明细胞腺癌
细胞类型	肿瘤细胞
形态学	成纤维细胞
生长方式	贴壁
倍增时间	大约24~31.11小时
培养基和添加剂	McCOY's 5A（中乔新舟  货号：ZQ-1000）+10%胎牛血清（中乔新舟 货号：ZQ0500）+1%P/S（中乔新舟 货号：CSP006）
推荐完全培养基货号	ZM0067
生物安全等级	BSL-1
STR位点信息	Amelogenin: X D3S1358: 15,18 TH01: 9.3 D21S11: 32.2,33.2 D18S51: 13,15 Penta_E: 13,16 D5S818: 11,13 D13S317: 11 D7S820: 11 D16S539: 11,13 CSF1PO: 10,15 Penta_D: 8,13 vWA: 16,17 D8S1179: 14 TPOX: 8,12 FGA: 21 D19S433: 15,15.2 D2S1338: 17,23
培养条件	95%空气，5%二氧化碳；37℃
抗原表达/受体表达	***
基因表达	***
保藏机构	ATCC; CRL-1978 BCRC; 60067 BCRJ; 0080
供应限制	仅供科研使用

货号	ZQ0067
发货规格	活细胞：T25培养瓶*1瓶或者1ml 冻存管*1支（细胞量约为5 x 10^5 cells/vial）二选一
发货形式	活细胞：常温运输；冻存管：干冰运输
储存温度	活细胞：培养箱；冻存管：液氮罐
产地	中国
供应限制	仅供科研使用

1、论文标题： Six-transmembrane epithelial antigen of the prostate 1 expression promotes ovarian cancer metastasis by aiding progression of epithelial-to-mesenchymal transition
DOI： 10.1007/s00418-020-01877-7
发表时间： 2020-05-07
期刊： HISTOCHEMISTRY AND CELL BIOLOGY
影响因子： 4.304
货号： ZQ0067
产品名称： ES-2 cells

原文链接： https://link.springer.com/content/pdf/10.1007/s00418-020-01877-7.pdf

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Cell 163:202-217(2015)

3、PubMed=26589293; DOI=10.1186/s13073-015-0240-5
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Cancer Cell 31:225-239(2017)

6、PubMed=28273451; DOI=10.1016/j.celrep.2017.02.028
Medrano M., Communal L., Brown K.R., Iwanicki M., Normand J., Paterson J., Sircoulomb F., Krzyzanowski P.M., Novak M., Doodnauth S.A., Suarez Saiz F.J., Cullis J., Al-awar R., Neel B.G., McPherson J., Drapkin R.I., Ailles L., Mes-Masson A.-M., Rottapel R.
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7、PubMed=30485824; DOI=10.1016/j.celrep.2018.10.096
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Integrated genomic, epigenomic, and expression analyses of ovarian cancer cell lines.
Cell Rep. 25:2617-2633(2018)

8、PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747
Dutil J., Chen Z.-H., Monteiro A.N.A., Teer J.K., Eschrich S.A.
An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines.
Cancer Res. 79:1263-1273(2019)

9、PubMed=30971826; DOI=10.1038/s41586-019-1103-9
Behan F.M., Iorio F., Picco G., Goncalves E., Beaver C.M., Migliardi G., Santos R., Rao Y., Sassi F., Pinnelli M., Ansari R., Harper S., Jackson D.A., McRae R., Pooley R., Wilkinson P., van der Meer D.J., Dow D., Buser-Doepner C.A., Bertotti A., Trusolino L., Stronach E.A., Saez-Rodriguez J., Yusa K., Garnett M.J.
Prioritization of cancer therapeutic targets using CRISPR-Cas9 screens.
Nature 568:511-516(2019)

10、PubMed=31068700; DOI=10.1038/s41586-019-1186-3
Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C., McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X., Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F., Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R., Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C., Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A., Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D., Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L., Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A., Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D., Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M., Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R., Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A., Sellers W.R.
Next-generation characterization of the Cancer Cell Line Encyclopedia.
Nature 569:503-508(2019)

11、DOI=10.26502/ogr072
Devor E.J., Lapierre J.R., Bender D.P.
ES-2 ovarian cancer cells present a genomic profile inconsistent with their reported history.
Obstet. Gynecol. Res. 4:233-238(2021)

12、PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010
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Pan-cancer proteomic map of 949 human cell lines.
Cancer Cell 40:835-849.e8(2022)